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Tagged: germline mutations

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13 years ago

Why is it said that cancer is a genetic disease?

Mike Birrer
Directory:
Cancer
Tags:
age
DNA
DNA damage
germline mutations
mutation
somatic mutation
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13 years, 1 month ago

What does BRCA deficiency mean?

Mike Birrer
Directory:
Cancer
Tags:
BRCAness
fanconi DNA repair pathway
germline mutations
ovarian cancer
p53
PARP inhibitors
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13 years, 1 month ago

How do PARP inhibitors induce synthetic lethality?

Mike Birrer
Directory:
Cancer
Tags:
BRCA1
BRCA2
breast cancer
DNA damage
germline mutations
homologous recombination
ovarian cancer
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