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Hair loss with chemotherapy is emotionally difficult for patients. However, most chemotherapy drugs may not cause hair loss. Even in those that do, one can use something called a cold cap to prevent hair loss from happening. The reason chemotherapy causes hair loss is because the chemotherapy drugs travelling in the bloodstream can affect hair roots and inhibit hair follicles from dividing; thereby causing hair loss. The cold cap uses the cold to switch off the blood vessels to the scalp. This diverts the chemotherapy agents away from the hair roots and therefore for many people there is no hair loss that follows from chemotherapy