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Professor Alice Smith

Professor of Lifestyle Medicine, University of Leicester

Professor Alice Smith leads the Leicester Kidney Lifestyle Team, a large multidisciplinary research group which aims to help kidney patients achieve the best possible health and wellbeing through appropriate lifestyle management. The team strive to produce high quality research and to involve patients, carers, healthcare professionals and stakeholders as partners to ensure delivery of research that meets the needs and expectations of our ultimate user-groups. Professor Smith’s research portfolio includes ~20 single- and multi-centre clinical trials, many of which are adopted on the NIHR portfolio, and have recruited some 6,000 participants since 2010.

Professor Smith’s primary research interest is the role of physical activity, exercise and lifestyle management in kidney disease. Her specific background is in inflammation and immune function but her translational research programme encompasses lab-based exploratory and mechanistic work, outcome measure evaluation, observational and epidemiological studies, clinical efficacy trials, lifestyle intervention development and effectiveness testing, implementation and service evaluation. A strong track record of patient involvement and engagement, and qualitative exploration of patient perspectives and experience underpins all the work.


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This two day international conference brought together experts, leaders and innovators working in exercise medicine to discuss their latest research. Delegates left the conference with an increased understanding of how to encourage physical activity within their communities, and help beat the biggest public health issue of our time.

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Keen to provide a lasting legacy of the 2012 London Olympic Games, the UK Government funded a new Institute of Sport, Exercise and Health based at University College London

The Institute is expected to increase exercise in the community and develop strategies to prevent diseases related to inactivity.

Dr. Mike Loosemore, a leading sports physician based at the new Institute, advocates that activity rather than exercise is a crucial, but an underused therapy to prevent, manage and treat many medical conditions.

According the Dr. Loosemore, "We need to increase our daily activity. We spend most of our working day sitting and sedentary behaviour is more damaging to health than smoking."

Dr. Loosemore spends much of his time with elite athletes, but believes that an important legacy of the London Olympics is to encourage everyone to increase their activity no matter how small.

"People need to increase their daily activity" he says, "because bouts of intensive exercise do not compensate for sitting for hours. We should focus on increasing the small movements we do every day. Anyone can increase their activity. It doesn't cost anything, it can be done anywhere at any time and it is sure to benefit your health and wellbeing. I'm surprised governments haven't latched onto this." Is Dr. Loosemore right?

 

Health systems treat illnesses rather than change peoples' behaviour

Our health and longevity are influenced by our genetics, environment and behaviour. We have little control over our genetics and environmental risks are reduced through vaccinations.

The only factor we control is our behaviour. Prompted by escalating healthcare costs, Western governments have successfully changed peoples' behaviour towards smoking. Healthcare systems however, are not focused on changing peoples' behaviour before they become ill, but on diagnosing and treating peoples' illnesses.

Exercise is Medicine is a movement that does emphasise the importance of behaviour. Launched in 2007 by the American College of Sports Medicine and the American Medical Association, it is dedicated to changing peoples’ behaviour towards exercise, which it suggests is crucial to the prevention, management and treatment of type 2 diabetes, heart disease and cancer.
 

Couch potato syndrome kills

A 2011 survey conducted by Tata Steel suggested that British children are likely to become a generation of couch potatoes who cannot swim, run or cycle.

The study of 1,500 children aged between six and 15 revealed that half the children surveyed lived sedentary lives and spent their time surfing the internet, chatting on social networks and playing video games.

Couch potato syndrome is a significant global challenge and it can kill. Emerging research evidence suggests that sedentary behaviour effects human metabolism, physical function and health outcomes.
 
When you sit, the electrical activity in your muscles become constant, your body uses little energy and slows down.

The take home message is simple: Sedentary lifestyles lead to weight gain, higher blood sugar and blood pressure levels, which increase your risk of heart disease, diabetes, obesity and cancer compared with those who sit less. 
 

Nothing compensates for long periods of inactivity

A challenge for traditional activity and obesity research is that it relies on self-reporting and people significantly under estimate how long each day they sit.

In 1999 researches from the US Mayo Clinic, challenged long-held beliefs about human health and obesity. Drs. James Levine and Michael Jensen addressed the question, why do some people who consume the same amount of food as others gain more weight?

After assessing how much food each of their research subjects needed to maintain their current weight, they banned exercise and gave all their subjects an extra 1,000 calories per day. This resulted in some gaining weight while others gained little to no weight.
 
The reasons for the difference were not apparent until six years later when the researches employed motion-tracking underwear.

"The people who didn't gain weight were unconsciously moving around more," Dr. Jensen says. "Their bodies simply responded naturally by making more small movements than they had before the overfeeding began, such as taking the stairs, helping with chores, standing rather than sitting and simply fidgeting."

On average, the subjects who gained weight sat two hours more each day than those who had not. Drs Levine and Jenson's research goes against conventional wisdom, which suggests that if you control your diet and exercise regularly, you can compensate for a sedentary lifestyle. This, they argue, is untrue and, "is like suggesting that the effects of smoking can be compensated by jogging"

Levine and Jenson's findings are supported by researchers from the American Cancer Society who found that benefits from regular daily exercise can be undone if you spend the rest of your time sitting.

Research on inactivity suggests that those who sit for prolonged periods have a higher risk of disease than those who move their muscles every now and then in a non-exercise manner. Also, those who sit for six hours or more have an 18% higher death rate than people who sit for three hours or less a day.
 
Sitting seems to be an independent pathology. Sitting for long periods is bad for your health whether you watch television afterwards or go to the gym. Dr. Mike Loosemore is right: excessive sitting is a lethal activity. 

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