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Mike Birrer

Vice chancellor and director, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences



Bevacizumab (trade name Avastin) is e drug produced by Genentech/Roche and it blocks the formation of new blood vessels, a process called angiogenesis. It is commonly used to treat various cancers, including colorectal, lung, breast, kidney, and glioblastomas.

Bevacizumab is a humanized monoclonal antibody that inhibits vacular endothelial growth factor A (VEGF-A) VEGF-A is a chemical signal that stimulates angiogenesis in a variety of diseases, and is particularly important in cancer.

 

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